Friday

October 2

SESSION TWO

4:00 – 4:20

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OBJECTIVES FOR DERMATOLOGICAL TOXICITIES OF ANTI-EGFR THERAPIES IN CANCER

Dr. Mario E. Lacouture

1. Recognize clinical and histological characteristics of dermatological
   toxicities to targeted therapies in cancer.
2. Understand mechanisms involved in dermatological toxicities to
   targeted therapies in cancer.
3. Apply mechanistically-based interventions towards these
   cutaneous toxicities in cancer.

Program Outline

1. The importance of cutaneous toxicities in EGFRI therapy
   a. Agents targeting the EGFR
   b. Frequency of toxicities
   c. Impact on patients and continued therapy
2. Characteristics of skin toxicities to EGFR inhibitors
   a. Clinical presentation
   b. Mechanisms
   c. Management
3. Future directions
   a. Toxicities to multitargeted agents
   b. Improvements in patient care

Mario E. Lacouture, M.D.
SERIES Clinic
Assistant Professor
Department of Dermatology
Robert H. Lurie Comprehensive Cancer Center
Northwestern University
Email m-lacouture@northwestern.edu.

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